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The results from SUSTAIN-1, the first phase 3a trial for Semaglutide, a new GLP-1 analogue administered once-weekly were presented. The trial investigated the efficacy and safety of 0.5 mg and 1.0 m ...


Patients with type-2 diabetes and cardiovascular disease can safely take the antihyperglycemic drug Sitagliptin ( Januvia ) without an increased risk of cardiovascular complications, even if they have ...


Positive top-line results from EMPA-REG OUTCOME were announced. This is a long-term clinical trial investigating cardiovascular ( CV ) outcomes for Jardiance ( Empagliflozin ) in more than 7,000 adult ...


The aim of a study was to identify risk factors for the development of statin-associated diabetes mellitus ( DM ). The study was conducted in two phases. Phase one involved high-throughput in silic ...


In the first U.S. safety trial of a new form of immunotherapy for type 1 diabetes ( T1D ), led by UC San Francisco researchers and physicians, patients experienced no serious adverse reactions after r ...


Reliable quantification of the association between blood pressure and risk of type 2 diabetes mellitus is lacking. A study sought to determine the association between usual blood pressure and risk of ...


Empagliflozin ( Jardiance ) has significantly reduced the risk of the combined endpoint of cardiovascular death, non-fatal myocardial infarction or non-fatal stroke by 14% when added to standard of ca ...


Omarigliptin, an investigational once-weekly DPP-4 inhibitor in development for adults with type 2 diabetes, has achieved its primary efficacy endpoint in a phase 3 study. Omarigliptin was found to be ...


Oral glucose-lowering medications are associated with excess risk of heart failure ( HF ). Given the absence of comparative data among drug classes, researchers have performed a retrospective study in ...


Cardiovascular autonomic diabetic neuropathy ( CAN ) is a serious complication of diabetes. No reliable data on the prevalence of cardiovascular autonomic neuropathy among patients with newly diagnose ...


Low levels of serum 25-hydroxyvitamin D [ 25(OH)D ] are commonly found in type 2 diabetes. Researchers have examined whether there is an association between circulating 25(OH)D concentrations and th ...


The aims of the study were to investigate weight loss and glycemic control parameters after different bariatric surgical procedures in type 2 diabetes ( T2D ) obese patients and identify patients' fac ...


Hypertension is a common diabetes comorbidity that affects the majority of patients, with the prevalence depending on type of diabetes, age, obesity, and ethnicity. Hypertension is a major risk fact ...


Combination treatment with a glucagon-like peptide-1 ( GLP-1 ) agonist and basal Insulin has been proposed as a treatment strategy for type 2 diabetes mellitus that could provide robust glucose-loweri ...


The efficacy and safety of Lixisenatide ( Lyxumia ), a once-daily prandial glucagon-like peptide-1 ( GLP-1 ) receptor agonist, in older patients with type 2 diabetes mellitus ( T2DM ) insufficiently c ...